Akebia Therapeutics, Inc. is a biopharmaceutical company focused on the development of small molecules for the treatment of anemia and vascular diesease. The company’s lead compound, AKB-6548, is a HIF-PH inhibitor in Phase I clinical trials for anemia. Akebia also has a platform of novel HPTPbeta inhibitors/Angiopoietin 2 modulators which have dmonstrated preclinical proof of concept in vascular leak, angiogenesis and as anti-metastatic agents. The first product to be developed from this platform, AKB-9778, is in late-stage preclinical development. Akebia is based in Cincinnati, Ohio, and is backed by a national syndicate of leading investors.
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